His other work includes series such as Big Apple (2001), Charlie Jade (2005), and The Nine (2006–2007).

Pierce was born Jeffrey Douglas Plitt in Denver on December 13, 1971.

Pierce made his acting debut in 1997, at the age of 25, playing Bill Drake in the Pacific Blue episode "Soulmate".

[citation needed] He played the title role in the 2005 science-fiction series Charlie Jade.

Pierce provided the voice and motion capture for Tommy in the video game The Last of Us (2013), which became his most prominent role.