Highly inspired by Robert Rodriguez's Rebel Without A Crew, the Soskas sought out El Mariachi star Carlos Gallardo to play the character God.

An absurdist dark satire, Dead Hooker in a Trunk originated as a faux trailer the sisters created, annoyed when their film school cut the budget for their final project.

[2][18] The twins cast Canadian horror star Katharine Isabelle (Ginger Snaps) as Mary Mason, and had special effects created by Masters FX.

Wanting to be respectful to the body modification community, the sisters hired flesh artist Russ Foxx as a consultant to ensure authenticity.

"[19] The sisters directed a segment in ABCs of Death 2 titled "T is for Torture Porn", which follows an actress, Yumi, as she auditions for an adult film scene.

[citation needed] The Soskas co-wrote and directed Rabid (2019), a remake of David Cronenberg's 1977 film of the same name,[21] starring Laura Vandervoort[22] and professional wrestler CM Punk.

[citation needed] In September 2022, the Soskas announced the premiere of their new film On the Edge, to take place at the London FrightFest Halloween festival on October 29.

The festival synopsis of the film reads, "Family man Peter gets more than he paid for when he books a 36-hour session with the sadistic Mistress Satana who seems more intent on making him suffer for his sins.

The Yaira #1 preorder campaign broke company records making a million dollars within 24 hours of launch[citation needed].