[3] Estrada did not play in a game in 2020 due to the cancellation of the minor league season because of the COVID-19 pandemic.

On August 30, 2022, Estrada was selected to the 40-man roster and promoted to the major leagues for the first time as a COVID-19 replacement player.

[5] Estrada made his MLB debut that night against the Toronto Blue Jays, striking out two in a scoreless innings of relief.

[10] From May 23 to 28, 2024, Estrada struck out 13 consecutive batters, setting an MLB record since the expansion era.

[11] He threw 53 consecutive pitches to those 13 batters, without a single ball being put in play, and without allowing a base runner.