Jeremiah S. Hess was an American politician who served in the Pennsylvania Senate for the 18th district representing Northampton County as a Democrat.

He then attended lectures in universities in Berlin, Bonn, and Tubingen but would be forced to abandon his theological studies due to poor health and return to the United States.

He worked as a cashier for the Saucon Savings Bank from 1873 to 1877 and became the Superintendent of the Christ Union Sunday School in Hellertown.

Hess would then be elected to the 18th district of the Pennsylvania Senate as a Democrat, serving for a single term from 1883 to 1886.

During his time in senate he would be a part of the Education, Insurance, Legislative Apportionment, and Library committees.