He is best known as the host of his BBC Radio 2 lunchtime programme which presents news, views, interviews with live guests, consumer issues and popular music.

[3] He is the elder son of Guy Vine (1937–2018),[4] lecturer in civil engineering at North East Surrey College of Technology, and Diana (née Tillett), who was a housewife and later a doctor's receptionist.

[7] Following a short stint on Metro Radio,[7] Vine enrolled in a journalism training course with the Coventry Evening Telegraph,[10] before joining the BBC in 1987.

[11] Vine's career at the BBC included reading the news on the radio in Northern Ireland and working as a researcher on the BBC1 series Heart of the Matter.

While working for Today, he published two comic novels set amidst the modern Church of England, including Forget Heaven, Just Kiss Me (1992) and The Whole World in My Hands (1993).

The film won the Silver Nymph at the Monte Carlo Television Festival and resulted in the suspension of 22 police officers.

In July 1999, the BBC announced that Vine was joining Newsnight full-time as a co-presenter, having stood in for Jeremy Paxman over the two previous summers.

In May 2006, Vine was announced as Peter Snow's replacement for presenting the BBC election graphics, including the famous Swingometer.

Between 2007 and 2010, Vine was the presenter of the BBC's flagship and the world's oldest current affairs programme, Panorama, which coincided with the show's move back to a Monday peak-time slot.

[21] In March 2021, it was announced that Eggheads would be joining his morning current affairs/phone-in show as a programme broadcast on Channel 5, after the BBC put the quiz on hiatus.

[22] On 6 January 2003, after several stints as a stand-in for Jimmy Young on BBC Radio 2, Vine took over the weekday lunchtime show on a regular basis.

Monday's The Health and Wellbeing Hour included either general practitioner Sarah Jarvis or Rabbi Julia Neuberger, while Friday's Your Money and Your Life, involves a variety of contributors, most frequently Martin Lewis.

[25][26] On 10 August 2015, Vine was the first celebrity to be announced as taking part in the thirteenth series of the popular BBC One competition Strictly Come Dancing.

On the fourth week of the contest, after Vine danced a jive to Bobby Darin’s "Splish Splash", Bruno Tonioli described him as a "Peculiar, off-the-wall artist like Tracey Emin", and Craig Revel Horwood compared him to "a stork that had been struck by lightning."

Campaign Against Arms Trade lodged a formal complaint with the BBC, claiming a conflict for the organisation appearing to support an industry which "profits from dictatorships which silence and suppress debate".

The differential was defended in part by a BBC executive referring to Vine having had a "glint in his eye" and a "cheeky" and light-hearted presentation style.

[33] On 25 May 2023, a post from the "Jeremy Vine on 5" Twitter account asked if it was "time to crack down" on sick people claiming out-of-work benefits.

He has deplored what he sees as the marginalisation of Christians in British society, saying that "You can't express views that were common currency 30 or 40 years ago".

[47] Vine described Belfield as "the Jimmy Savile of trolling", and said he had been subjected to an "avalanche of hatred" and a "constant bombardment" of harassing tweets and YouTube videos.

[49] In May 2024, judge Mrs Justice Steyn in the High Court ruled in favour of Vine, who had sued former footballer Joey Barton for libel over posts on Twitter; 11 of the 14 cited tweets were found to be defamatory.