He was married to Lilia Quindoza Santiago, a professor in Filipino literature at the University of the Philippines, and also an accomplished poet and writer.
Santiago translated Lu Xun's "Diary of a Madman", Arthur Miller's Death of a Salesman into the Filipino language, as well as some songs and poems of Latin American and African-Asian writers.
These albums include the songs Huling Balita (Last News), Martsa ng Bayan (March of the Nation), the lullaby Meme Na (Sleep Now) and Pitong Libong Pulo (Seven Thousand Islands).
His themes and the Filipino lower-class characters in his songs evolved from the political and social realities during the decade of Marcos despotism in the 1970s.
He also has a column Usapang Kanto (Street Corner Talk) on the pages of the Pinoy Weekly newspaper in the Philippines.