Jesse Bledsoe (April 6, 1776 – June 25, 1836) was a slave owner[1] and Senator from Kentucky.

When he was very young, his family migrated with a Baptist congregation through Cumberland Gap into Kentucky.

Afterwards he was elected as a Democratic Republican to the United States Senate and served from March 4, 1813, until his resignation on December 24, 1814.

He died near Nacogdoches, Texas under circumstances his contemporaries and kinfolk could only describe as a significant fall from grace.

Besides being a prominent jurist, he was a maternal uncle to many notable individuals including, but not limited to, Robert Emmett Bledsoe Baylor, who studied law under him, Walker Keith Baylor, who served in both chambers of the Alabama Legislature and as a judge, Thomas Chilton, who likewise represented Kentucky in Congress, and William Parish Chilton, a provisional congressman of the Confederacy from Alabama.