Jesse Eugenio Mercado (born June 6, 1951) is the first bishop of Roman Catholic Diocese of Parañaque.

He studied at St. Joseph School and completed his philosophical and theological formation at the Jesuit-run San Jose Seminary.

There, he served as Assistant Parish Priest (1977) of San Isidro Labrador Parish in Pasay, Spiritual Director (1977–1979) at the San Pablo Regional Seminary in Baguio City , Director of the Pre-College Department of the San Carlos Seminary (1979–1981), Professor of Theology (1985–1988) at the San Carlos Seminary, Rector (1988–1994) of the Holy Apostles Senior Seminary , and Rector (1994–1997) of the Pontificio Collegio Filippino.

Pope John Paul II named him as Titular Bishop of Talaptula and Auxiliary Bishop of Manila on February 25, 1997, and was ordained on March 31 of the same year.

Pope John Paul II subsequently appointed him as the first and founding bishop of the Diocese of Parañaque on 7 December 2002 and formally installed on 28 January 2003.