[1] Guzman was born to David C. and Ella Roberts Parkhurst in Savannah, Georgia.
[2] Reverend Doctor John Percy Wragg was a clergyman who led the American Bible Society's Agency Among the Colored People of the South.
[5] After working as John Wragg's private secretary, Guzman taught history at New Orleans College from 1922-1923.
She briefly taught at Alabama State Teacher's College during the 1929-1930 academic year and then returned to the Tuskegee Institute where she worked until her retirement in 1965.
[5] From 1938–1944 Ms. Guzman was the Dean of Women at the Institute, and then in 1946 became the Director of the Department of Records and Research — a successor in her own right to Monroe Work’s legacy.