In the succeeding years, she played supporting roles in a series of television shows including Natutulog Ba Ang Diyos?

Jessy's younger sister Megan was born in Mexico, where her parents reconciled but eventually separated again for unknown reasons.

Mendiola revealed that she was pulled out of Habang May Buhay and was cast as Christina in the TV series Kung Tayo'y Magkakalayo instead.

[10] Mendiola was supposed to appear in Habang May Buhay and was featured in the 2008 trailer of the show which was originally titled as Humingi Ako sa Langit.

Mendiola was supposed to appear in Kokey @ Ako, opposite Enrique Gil, but their characters were written off in favor of Melai Cantiveros and Jason Francisco.

[18][19] Earlier, she portrayed Isabel Valderama in Agimat: Ang Mga Alamat ni Ramon Revilla Presents: Bianong Bulag.

[20][21] She also played the role of Jacqueline Marasigan in the primetime TV show, Budoy, opposite Gerald Anderson and Enrique Gil.

She also starred in the afternoon TV show Precious Hearts Romances Presents: Paraiso, with Matteo Guidicelli, Matt Evans and Jewel Mische.

[25] In 2015, Mendiola played another lead role in the comedy drama Must Date the Playboy, alongside Kim Chiu, Xian Lim and Matt Evans.

and in the romantic family drama You're My Home, alongside Dawn Zulueta, Richard Gomez and JC de Vera.