[4] When his elder brother, Don, left his position as the host and announcer for The Chase and Sanborn Hour in the early 1940s, Jim took over for the remainder of the show's run.

Other shows Ameche was heard on included Grand Hotel, Hollywood Playhouse, and Big Sister.

By the late 1960s, he was working as an announcer on New York's WHN and the TV pitchman for a Longines Symphonette Society mail-order record album featuring clips of old-time radio broadcasts.

For many years, he was the afternoon announcer on WQXR, the classical radio station of The New York Times, and was a familiar and beloved voice.

[5] Jim Ameche died February 4, 1983, of lung cancer at Tucson Medical Center at age 67.