The player is able to play as Kermit and Animal and must travel through different eras time to save the rest of their friends.

The game features six zones with a time travel theme, spanning the prehistoric era to the wild west.

Gameplay involves navigating levels to find keys, energy and other bonuses, and using projectiles, such as paper planes and drumsticks, to defeat enemies.

[3] Game Boy Xtreme stated Muppets was a "terrible platformer with use of colour and poorer playability".

[5] Milder reviews included those from Nick Woods of Allgame, who described the game as a "suitable choice for smaller kids", whilst noting "the rest of the gameplay is not unique".