Muppets Party Cruise is a 2003 party video game, based on The Muppets franchise, developed by Mass Media and published by TDK Mediactive for the PlayStation 2 and GameCube.

This was the Muppets' last video game before the franchise was acquired by The Walt Disney Company in 2004.

Muppets Party Cruise has six playable characters: Kermit, Piggy, Fozzie, Gonzo, Animal and Pepe, and six non-playable characters: Statler and Waldorf, Rowlf, Rizzo, Swedish Chef, Sam the Eagle, Bunsen and Beaker.

The game contains 30 mini-games, 15 of which the player must unlock,[2] and five levels: the Engine Room, Crew's Quarters, Quality Cabins, Star Suites and Royal Staterooms.

[5] In "short cruise" mode, the first player may select a mini-game in which everyone will compete, but no party favors are won.