[4] Zayner found NASA's scientific work less innovative than she expected, and upon leaving in January 2016, she launched a crowdfunding campaign to provide CRISPR kits to let the general public experiment with editing bacterial DNA.

Zayner also continued their grad school business, The ODIN, which sells kits to let the general public experiment at home.

[2] Zayner self-identifies as a biohacker and believes in the importance of letting the general public participate in scientific experimentation, rather than leaving it segregated to labs.

Other scientists have responded that biohacking is inherently exclusive for its dependence on leisure time and money, and that deviance from general safety rules could lead to even harsher regulations for all.

[8] Zayner maintained that these fears were based on misunderstandings of the product, as genetic experiments on yeast and bacteria cannot produce a viral epidemic.

[9][10] In April 2015, Zayner ran a hoax on Craigslist to raise awareness about the future potential of forgery in forensic genetic testing.

[2] This experiment was documented by filmmakers Kate McLean and Mario Furloni and turned into the short documentary film Gut Hack.

In 2020, Zayner, David Ishee and Dariia Dantseva, who form a group of Biohackers named The Central Dogma Collective (CDC) tested a DNA based coronavirus vaccine on themselves and live-streamed the whole process and made all protocols and data open source and freely available to the public.