[2] At MIT, he designed and built an autonomous, robotic system that enables research into ocean circulation patterns and climate change, by operating untended for up to one year at sea on battery power and collecting hyper-pure water samples at predetermined intervals.

[12] Betts-LaCroix has participated in the Quantified Self movement since the beginning,[13] and has given numerous presentations on aspects of self experimentation and tracking, including experiments in the 28-Hour day.

The underlying goal of Halcyon's work was to make meaningful progress in understanding human biology in order to improve medicine.

[16] The efforts of the people working in Health Extension are motivated by recognizing that In 2013, Betts-LaCroix cofounded Vium, which has raised $33M to accelerate the development of new medical therapies by automating in-vivo research.

[24] In 2020, Betts-LaCroix cofounded Retro Biosciences, which emerged out of stealth with $180 million in funding from OpenAI CEO Sam Altman[25] to focus on extending healthy human lifespans.