In 1999, Pasquale made his stage acting debut in Larry Shue's The Nerd before playing Guildenstern in a UK tour of Tom Stoppard's Rosencrantz and Guildenstern Are Dead in 2004 and in 2007, Pasquale played Leo Bloom in the UK tour of Mel Brooks' musical The Producers opposite Cory English and Russ Abbot.

Pasquale joined Bradley Walsh, Brian Conley and Shane Richie as part of "The Prat Pack" for a one-night-only sold-out concert at the London Palladium on 30 March 2024.

[6] In January 2013, Pasqaule became one of twelve celebrities participating in the eighth series of Dancing on Ice, with skating partner Vicky Ogden.

[citation needed] Pasquale also provided the voice over for Underdog, a cartoon dog mascot of personal injury firm National Accident Helpline.

[13] On 5 August 2023, Pasquale revealed on Kate Thornton's White Wine Question Time podcast that he had accidentally impaled himself on a pair of prop moose antlers in Skegness.

[14][15] Pasquale, 61 at the time, described himself as "lucky to be alive", and recalled having tripped initially but then contorting evasively as he fell "like Tom Cruise in the new Mission Impossible film" to avert greater injury.