Reed is best known for directing the controversial Blood Sucking Freaks [5] (1976), a notorious horror comedy that was the subject of protests upon its initial release and has since achieved cult status.

Executioner (Wit's End / Dragon Lady / Wild Dragon Lady;[7] 1971), Blood Bath (Terror / Night and the City;[7] 1976),Blood Sucking Freaks [8] (1976) and Night of the Zombies (Gamma 693 / Sister of Death / Battalion of the Living Dead;[7] 1981).

[9] Reed wrote and directed Blood Bath, which was produced by the Trans-Orient Entertainment Corporation and had a budget of $100,000.

In 2011 Reed made a comeback as an actor playing the main character Uncle Joe in the film Dead Eye, directed by Louis Affortunato.

After that, Reed acted in eight more films: I Spill Your Guts (2012); Supernaturalz: Weird, Creepy & Random (2012); Trashtastic (2013); Catch of the Day (2014); The Fappening (2015); Vault of Terror II: The Undead (2015); Freak in a Basement (2018); and The Dysfunctional Mob.