Johan Gustaf Acrel (May 15, 1741 – February 18, 1801) was a Swedish physician and Professor of Medicine at Uppsala University.

He became a Master of the Society of Surgeons (Kirurgiska societeten) in Stockholm 1763.

Back in Uppsala his reputation grew as one of Europe's finest physicians.

In 1788 he was appointed Professor of Practical Medicine at Uppsala University, and in 1779 he was made a Member of the Royal Swedish Academy of Sciences.

He was also Rector Magnificus of Uppsala University during the spring of 1796.