Having moved to Amersfoort he became interested (under the influence of Jacob van Campen) in architecture, until his college friend Constantijn Huygens got him a position as professor of botany and literature in a newly founded academy in Breda; he was also keeper of the botanical garden.
[2] A member of the Muiderkring,[3] the arts and sciences coterie whose central figure was P. C. Hooft, he was known as a "dilettante"[4] with an interest in natural philosophy (the work of Francis Bacon[5]) and a classical scholar,[1] and his interest in literature is proven in his scattered poems,[2] one of which a translation of Petrarch's Sonnet 213, "Grazie ch’a pochi il ciel largo destina".
[7] Van Brosterhuysen made a number of important friends, including people such as the humanist and theologian Caspar Barlaeus and poet P. C. Hooft,[2] and especially Huygens, a poet and composer and secretary to princes of the House of Orange: In 1634, he was able to cure (perhaps with a botanical remedy) Huygens's wife of kidney stones, and a Latin poem by Huygens dated 1627 thanks Brosterhuysen for advising him on horticultural matters.
He is credited with sixteen landscape etchings made, apparently, at Randenbroek, the country estate of artist and architect Jacob van Campen near Amersfoort.
[8] His landscapes display "with a distinctive sensibility towards trees and foliage and few indications of human presence".