He came to prominence through his efforts to promote agricultural reforms, especially with his 1769 publication with new regimes of crop rotation,[3] and his 1773 textbook on rural householders and husbandry.
[5] From 1737 to 1740 he took his theological studies at the University of Jena,[2] where he was influenced by the philosopher Christian Wolff and the Swiss anatomist, physiologist and naturalist Albrecht von Haller.
In 1768 he published his findings for the first time in his book, entitled Lehre vom Gyps als vorzueglich guten Dung zu allen Erd-Gewaechsen auf Aeckern und Wiesen, Hopfen- und Weinbergen (Doctrine of Gypsum exquisitely as good manure to all natural plants to the fields and meadows, hops and vineyards).
[2] In the 18th Century the pressure upon agriculture had increased to feed the steady growing population, and Mayer was one of the driving forces to make this happen.
[11] Mayer among others presented plans for a new farm house, the so-called "Pfarrer-Mayer-Häuser", in which the rural residential area and the barn were under one roof.
[5] The 1804 Repertory of arts, manufactures and agriculture Richard Weston reports that "New manure appearing as an uncommon phenomenon in the Annals of Agriculture, it cannot be an uninteresting matter to disperse the knowledge of its valuable qualities, and how it came to be known, especially as it is now making a rapid progress into every enlightened country where the farmers are not above being taught from the ingenuity, labour, and researches of others, and of all the modern improvements in agriculture no one appears to be of greater consequence..."[12] The general description, Weston gave, started with: Weston further explains about experiments on various soils, its effects on grasslands, and a comparison between dung and plaster.
[12] Weston explicitly mentioned, that "it is to the indefatigable researches of Mr. Mayer, a German clergyman, that we are indebted for this valuable fossil as a manure; but where his residence is I have not yet been able to discover, nor have seen any of his .writings concerning it.
As a proof of which, I have taken an account of the following experiments, from a book printed in that city, in French and English, but first published in various periodical works in Philadelphia, Pennsylvania, &c.; and from these American publications it was introduced into England, after having made a circuit of nearly ten thousand miles.
Early 19th century however a great variety of opinion remained with regard to its mode of operation, for example:[13] After being applied with success by Mayer in the year 1763, Gypsum soon came into general use, not only in Germany, but in France, America, Switzerland, and other countries.
The range of subjects treated by him is great from topics classified under the purely agricultural engineering to cultivation, fertilization, harvesting, livestock, etc.
But he, again and again, focussed his writings on social ethical and diaconal questions of his town, and openly criticized that rural life would be better served with dutiful authorities and philanthropic landowner.