Johannes Acronius Frisius (1520 – 18 October 1564) was a Dutch medical doctor and mathematician of the 16th century.
He was named after his city of birth, Akkrum in Friesland.
He died from the plague in the same year.
Apart from mathematical and scientific works, he wrote Latin poetry and humanist tracts.
According to the Historical Dictionary of Switzerland, "nothing justifies the usual identification of A[cronius] with the philologist and botanist Johannes Atrocianus".