He came from a family of artists and he lived with his sister Elizabeth Byrne who also exhibited her landscapes.
He was the only son of engraver William Byrne and followed his father's profession in the arts.
She created six steel engravings for Thomas H. Shepherd's "Modern Athens".
[4] He subsequently concentrated on landscape painting in watercolours; his sister Mary and her son were also painters.
He sent pictures to the exhibitions of the Water-Colour Society and the Royal Academy; and spent some years (about 1832–37) in Italy.