He is most well known for performing the first transfemoral and the first transapical transcatheter aortic valve implantation in the world both in 2005.
John G. Webb completed his undergraduate education at Simon Fraser University and graduated with his BSc (Hons) in Biology in 1978.
He completed a two-year fellowship in cardiology at the University of Toronto Faculty of Medicine and went to the University of California San Francisco for a two-year interventional cardiology fellowship as a Canadian Heart Foundation fellow.
[7] After the world's first transcatheter aortic valve implantation was performed using an antegrade transseptal approach by Prof. Alain Cribier in 2002 at the University of Rouen, Webb developed the transapical and retrograde transfemoral transcatheter aortic valve implantation in 2006 at St. Paul's Hospital in Vancouver.
[8][9] The transfemoral and transapical approach are now the two most common access routes used in TAVI today.