He started 36 games and recorded 275 knockdowns and 34 touchdown-resulting blocks during his three seasons at left tackle.

In 2007, he started all 12 games for Toledo and earned First-team All-MAC for the third consecutive season and was a Third-team All-America by Rivals.com after allowing only three sacks on 411 pass plays.

As a junior in 2006 he was the team co-captain started all 13 games at left tackle, earning First-team All-MAC honors.

He spent 2008 as a backup; due to injuries he started one game at the end of the 2008 NFL season.

He played very well, finishing among the highest ranked guards in the league for blocking percentage.

[3][4] On October 12, 2014, Greco played at center for the first time of his career after Alex Mack left due to a broken fibula.