John Guise (1682 or 1683 – 12 June 1765) was a British Army officer and art collector.
He was educated at Christ Church, Oxford from 1702 to which he later bequeathed his large collection of over 200 paintings and almost 2,000 drawings by artists such as Leonardo da Vinci, Michelangelo and Raphael - one such work is Annibale Carracci's Madonna and Child in Glory over the City of Bologna.
In 1719 he was one of the original backers of the Royal Academy of Music, establishing a London opera company which commissioned numerous works from Handel and others.
In 1739 he was promoted to the rank of brigadier-general, and served as one of the senior officers during the unsuccessful Siege of Cartagena during the War of Jenkins' Ear in 1741.
This article incorporates text from this source, which is in the public domain: Historical Records of the British Army: The Sixth, or Royal First Warwickshire Regiment of Foot, p. 109 (1837).