[1] Shortly after this, he reincorporated Santorini, which had been ruled by Domenico Pisani, husband of his niece Fiorenza Crispo, into the Duchy.
[2] His raising of taxes made him very unpopular among the Greek population of Naxos, however.
Only the timely arrival of galleys from the Knights Hospitaller of Rhodes rescued Crispo and put an end to the revolt.
[1] The discontent did not subside, however, and in 1494 John was killed, apparently by poison, by the locals, who sent an embassy to Venice requesting for the Republic to assume control of the island, as John's sole heir, his son Francesco III Crispo, was underage.
He was married to a Morosini and had issue: Giovanni (John) also had a Mistress, his cousin, Maria Crispo, daughter of Anthony Crispo Lord of Syros (Sira).