[8][9] On October 14, 2008, McCargo was traded to the Indianapolis Colts for an undisclosed draft pick, having been beaten out in the depth chart by Kyle Williams.

However, after failing his physical the following day, the trade was voided and McCargo was returned to the Bills.

[12] In the 2009 season, he appeared in 11 games and made one start, which came in Week 10 against the Tennessee Titans.

[16] On November 8, 2011, the Buccaneers re-signed McCargo to fill a roster void caused by a season-ending injury to Gerald McCoy.

[18] A week later McCargo was once-again re-signed, following a season-ending knee injury to George Johnson.