John Nisbet, Lord Dirleton (c. 1609–1687) was a Scottish judge remembered for his prosecution of the Covenanters.
In 1634 he acted for John Toash, the master of household to James Crichton of Frendraught.
Nisbet argued successfully that the case against Toash was disproved by the conviction of another suspect, John Meldrum.
He was a commissioner for the union of Scotland and England in 1670, and was forced to resign his position as Lord Advocate in 1677.
His Edinburgh townhouse was on the Canongate at the head of Reid's Close, built in 1624 by his father, and distinguished by a square turret projecting over the pavement.