He left college early at the age of 16, to join the cast of the original UK tour of Andrew Lloyd Webber's musical Cats.

Later he joined the West End production of the show at the New London Theatre, playing the roles of Rum Tum Tugger and Munkustrap and in 1998, he appeared as Rum Tum Tugger in the official film production of the show, produced by Lloyd Webber and filmed at the Adelphi Theatre.

Partridge later returned to the West End cast of the show prior to its closure in 2002 and has also appeared as Rum Tum Tugger in the German production in Düsseldorf.

[2] Partridge's TV appearances include The Hot Shoe Show, a documentary called Aspects of Dancing, and BBC2 comedy Game On where he portrayed a predatory gay gym member attempting to chat up the sexually confused lead character Matthew.

[5] Partridge has worked with several rock and pop acts, including U2, Pet Shop Boys, Kim Wilde, Neneh Cherry, Pete Townshend, Mica Paris and Ultra Nate.

[6] In 2010, Partridge, together with Sheila Hancock and Charlotte Church, was one of the judges for the new Andrew Lloyd Webber TV show Over The Rainbow, in search to find a young girl to play Dorothy in a new production of The Wizard of Oz.

[9] On 12 December 2010 he appeared on All Star Family Fortunes to raise money for the Terrence Higgins Trust but lost to Caroline Flack.

[11] In July 2012, it was announced at a press launch that Partridge will be once again taking on the role of Prince Charming in Cinderella, this time at the Theatre Royal, Nottingham, which ran from 8 December 2012 until 13 January 2013.

[25][26] From August 2019 to April 2020 Partridge appeared in the UK Tour of Cabaret,[27] alongside Anita Harris and Kara Lily Hayworth.

He had kept the diagnosis secret due to fears of losing work, revealing it only to encourage men to screen and test for prostate and testicular cancer.