He thrived at the school, was awarded a post-secondary scholarship[1] and moved on to attend the University of Waterloo, studying engineering.

[2] He studied under the Toronto Workshop Productions theatre troupe and found acting work in film and television.

In 1967, Yesno took on the role of host and producer of the CBC's "Indian Magazine", later known as "Our Native Land", which presented the views of Indigenous Canadians weekly.

"[7] On his show, "we raise a few storms of our own on the program", "we expose bad situations when we find them, and also inform Indians what rights they have and what resources are open to them.

[5] In 1972, Yesno produced and hosted a week-long festival of Indigenous arts and culture at Toronto's Ontario Place.

[10] In 1975, Yesno acted in Cold Journey, a film about a young boy who runs away from residential school and is found frozen to death, similar to the 1966 real-life story of Charlie Wenjack.

He hoped that the arena would "bring both communities together at a crucial time when we seem to be splitting into different ethnic and social entities".

[12] Yesno was praised by Nishnawbe Aski Nation Grand Chief Stan Beardy, who stated "Yesno blazed a lot of trails for us" and he "educated society at a time when the Lone Ranger and Tonto was on television, about not stereotyping First Nation people.".