Josef Kyrle (8 December 1880 – 30 March 1926) was an Austrian pathologist and dermatologist who was a native of Schärding.
In 1907 he was an assistant to Ernst Finger (1856–1939) at the dermatology clinic in Vienna, and in 1918 he became an associate professor.
In 1916 Kyrle referred to this condition as hyperkeratosis follicularis et parafollicularis in cutem penetrans.
It is characterized by keratotic plugs that develop in hair follicles and eccrine ducts, penetrating the epidermis and extending into the dermis.
He performed investigations on the use of Jauregg's malaria therapy for treatment of syphilis in its early stages, and with Dr. Weichselbaum, he performed important studies involving the origin and development of the islets of Langerhans in the fetus.