[1] In July 1872, at the age of fourteen, Krauskopf emigrated to the United States, expecting to join his older brother, Manaseh, in New Jersey.

While not denying or renouncing his own faith, he attended the local Unitarian Church (there was no Jewish congregation in the city), and became a protégé of Mrs. Mary Bridges Canedy Slade, who was the assistant editor the New England Journal of Education, a well-known author and composer, and the wife of the principal of the local high school, Albion Slade.

In 1875 Mrs. Slade recommended him to Isaac Mayer Wise who was organizing the first rabbinical class at the newly founded Hebrew Union College in Cincinnati, Ohio.

Also writing a letter of recommendation for Krauskopf was William Reed, the editor of the Fall River Daily Evening News.

This was Krauskopf's first opportunity to enter a program of formal education since arriving in the United States three years earlier at the age of fourteen.

"[5] In 1899 both of his Hebrew readers were being sold through the "Educational Catalogue for 1899" advertised in the publishing industry trade journal, Bookseller, Newsdealer, and Stationer.

His Kansas City congregation tried to prevent him from leaving, and even state and local politicians pressured him to reject the offer from KI.

A talented and popular speaker, he drew as many as 1,000 listeners to his Sunday services, including non-members and non-Jews who came to hear him speak.

Following the intellectual lead of his teacher, Isaac Mayer Wise, he was committed to the study of Jewish-Christian relations and even attempted to reclaim the apostle Paul as a model for Judaism.

However, at this time, the American Jewish world was being transformed by massive immigration from Russia, Poland, and other parts of Eastern Europe.

This led to a resolution in Congress, proposed by Representative Isidor Rayner of Maryland, urging the United States to abrogate the existing treaty with Russia.

Krauskopf met with American diplomats, Russian political leaders and various intellectuals including Leo Tolstoy, best known as the author of War and Peace (1869) and Anna Karenina (1877).

On his return he worked to establish a similar institution outside of Philadelphia, believing that it would attract Jews from Russia and help provide them with an education to begin a new life in the United States.

Shortly after the outbreak of the Spanish–American War in 1898, Krauskopf became a leader of the National Relief Commission, and was one of three special field commissioners to visit army camps of the United States and Cuba.

During World War I Krauskopf continued his patriotic public service, working under Herbert Hoover in the U.S. Food Administration.

The Jews and Moors in Spain[10] came from a series of eighteen public lectures Krauskopf gave while he was the Rabbi at Congregation B'Nai Jehudah in Kansas City, Missouri.

Indicative of their popularity, and the political significance of Krauskopf's interfaith activities, the book had letters of endorsement from Thomas T. Crittenden, the former Governor of Missouri and U.S. District Judge Arnold Krekel.

If I had no other proof for my belief in the existence and sovereignty of an Intelligent Final Cause, I would derive it from my recognition of the fact that supreme order, uninterrupted harmony, eternal and immutable law, control all nature, heaven and earth, all inorganic and organic, in but one way, and in no other.

"[18] He acknowledged that Darwin "opposed" the "Biblical account" of creation,[18] because modern research proved the Biblical account of creation imperfect,"[19] But Krauskopf argued that this science, and Darwinian notions such as natural selection, actually supported the idea of a superior being – God – who set into motion evolution through natural selection.

"[21] Evolution and Judaism is also interesting because, at the same time as adopting a sceptical approach to traditional readings of the bible, Krauskopf attempted to justify Jewish religious continuity by presenting a Jewish form of panentheism that viewed the universe as an evolving phenomenon and presented a biological argument for the reality of life beyond death.

"[25] He argued that the Protestant Reformation led to "the slow return from the pagan Christ to the Judean Jesus, the gradual stripping away of the many foreign-borrowed accretions under which the Nazarene prophet and patriot had well-night been buried"[25] and thus "after eighteen hundred years of cruel separation, Christian and Jew are drawing closer to each other.

Krauskopf believed that Christianity – and especially the New Testament – had been corrupted by "foreign material and falsified history, of pagan mythology and Persian demonology and Egyptian mysticism."

[26] After her death Krauskopf was absorbed in professional duties and activities, including his trip to Russia and founding the National Farm School.

Rabbi Krauskopf's son, Manfred, served as the president of the board of trustees of the National Farm School, which his father had founded.