Juan Cruz Guasone (born 27 March 2001) is an Argentine professional footballer who plays as a centre-back for Italian Serie B club Salernitana on loan from Estudiantes.
Guasone had two-year spells in the youth ranks of Lanús and Rosario Central before joining Patronato in 2018; following a trial in 2017.
[2][3][4][5] He was moved into the club's first-team squad in 2020–21, with the centre-back initially appearing as an unused substitute for Copa de la Liga Profesional matches with Huracán and Gimnasia y Esgrima in November.
[6][7][8] His senior debut soon arrived in that competition later that month, on 29 November, during a 1–0 defeat away to Huracán; he played the full ninety minutes, picking up a yellow card in the process.
[6][9][10] On 14 January 2025, Guasone joined Salernitana in Italy on loan with an option to buy.