Soon after, the "Don Q" brand of rum became very popular in Puerto Rico and the family business began to grow.

Juan Serrallés died in 1921 just as the production of rum was being halted because of the United States Prohibition Act of the 1920s.

Juan Serrallés Colón married Mercedes Perez (1845–1922), after whom he named his sugar plantation.

Juan Eugenio built a huge castle in Ponce, called the Serralles Castle, for his three children some ten years after his father's death, a testament to the prosperity of the plantation business that Juan Serrallés had started the previous century.

Eventually one of these grandchildren, Felix Juan, became the next in line to run the sugar plantation and rum distillery businesses, which he did until his death in 1985.