The men's +100 kg judo competition at the 2008 Summer Paralympics was held on 9 September at the Beijing Workers' Gymnasium.

This event was the heaviest of the men's judo weight classes, allowing competitors with over 100 kilograms of body mass.

The tournament bracket consisted of a single-elimination contest culminating in a gold medal match.

The two judokas who lost in the semifinals faced the winner of the opposite half of the bracket's repechage in bronze medal bouts.

A twelfth competitor, Khalil Guerfa of Algeria, was disqualified for failing a pre-match medical exam.