The men's 100 kg judo competition at the 2008 Summer Paralympics was held on 9 September at the Beijing Workers' Gymnasium.

This event was the second-heaviest of the men's judo weight classes, limiting competitors to a maximum of 100 kilograms of body mass.

The tournament bracket consisted of a single-elimination contest culminating in a gold medal match.

The two judokas who lost in the semifinals faced the winner of the opposite half of the bracket's repechage in bronze medal bouts.

A twelfth competitor, Ahmed Kebaili of Algeria, was disqualified for failing a pre-match medical exam.