[1] Chance the Rapper sings and raps in a comedic manner;[2][3] his verses in the song have been described as having a "freewheeling, bluesy sway" that "gives way to raucous call-and-response choruses".

[4] He references the 1992 film Juice (of which the song's title originates) and playfully taunts the Los Angeles Lakers while warning about the pitfalls of being successful.

Craig Jenkins of Pitchfork wrote that it "finds Chance displaying better control of his abilities and treating the gear shift from rapping to singing less like the flick of a switch, as older songs did, and more like a pendulous drift."

[1][3] When Acid Rap was first re-released on streaming services on June 28, 2019, "Juice" was replaced with a 30-second spoken message, in which Chance the Rapper explains the song is excluded from the mixtape because of an uncleared sample.

Chance then adds that all streaming proceeds for the alternate version of "Juice" go directly to SocialWorks, a non-profit organization which he founded, and encourages listeners to replay the song all the way through for payment to be received.