[2] Tolentino was a member of the activist group ACT UP and appeared in the 1989 "Kissing Doesn’t Kill: Greed and Indifference Do" campaign with Lola Flash by the AIDS awareness artist-activist collective Gran Fury.
"[9] Tolentino co-wrote the Lesbian AIDS Project's Women's Safer Sex Handbook, and was a founding member of ACT UP New York's House of Color Video Collective.
[10] Since 1998, Tolentino has presented solo and group installations and performance work at the New Museum, PARTICIPANT INC, The Kitchen, and Performa, New York;[11] the Haus der Kulturen der Welt, Berlin;[12] La Batofar, Paris, France; Momenta and Monkey Town Gallery; Madre Museo, Naples, Italy; Walker Arts Center;[13] the Los Angeles Contemporary Exhibitions;[14] In 2013, Tolentino staged the solo exhibition Raised by Wolves at Commonwealth and Council in Los Angeles, which included over 50 intimate, interactive performances alongside a series of site-specific sculptures.
[15] In 2019, the artist mounted her second exhibition at the Koreatown gallery, REPEATER, an "immersive installation incorporating sculpture, video, and 108 hours of performance.
For the exhibition they collaborated with Ivy Kwan Arce to create a work with glass orbs, satellites, and performance.