[1] Restrepo began her acting career with the 2006 Colombian horror film At the End of the Spectra.

She acted in the Colombian films La semilla del silencio and Malcriados.

[4] As her roles varied from religious to a prostitute,[5] Colombian newspaper La Opinión described her as a versatile actress.

[8] In 2022, it was announced that Restrepo would star as the late Colombian suffragist and Senator Esmeralda Arboleda Cadavid in a film titled Estimados Señores (Dear Gentlemen).

[1] She moved to Los Angeles[11] to shoot her first English short movie, Do Not Lose.