On the request of community leaders, then Prime Minister Lee Kuan Yew helped to establish the school in 1961 as Jurong Integrated Secondary School.

Jurong Secondary School is located at 31, Yuan Ching Road.

The school has a niche area in sports – Basketball, Volleyball and cross-country running.

Recently, Jurong Secondary has been selected as one of FutureSchools@Singapore which means that Infocomm companies support the students in the chosen school who are interested in Infocomm, alongside Hwa Chong Institution and Crescent' Girls School.

The former Prime Minister of Singapore, Lee Hsien Loong, the Minister of State for Education, Lui Tuck Yew and as well as foreign visitors had visited the school.