After completing his education at a Hollandsch-Inlandsche School (HIS), he continued to a Meer Uitgebreid Lager Onderwijs (MULO), although his father, Kunto Wibisono, had wanted him to study to be a teacher.

He then continued to the Rechtshogeschool in Batavia, graduating with a Meester in de Rechten in 1941, shortly before the Japanese invasion of the Dutch East Indies.

[1][2] During his studies, Wibisono became active in the Jong Islamieten Bond youth organization, and in 1934 along with Mohammad Roem he co-founded a branch that catered to secondary students, the Studenten Islam Studieclub.

[3][2] He had begun to work at the colonial government before completing his law degree, first at the economic department and then in the central statistics office.

[7] After the conclusion of the Indonesian National Revolution, Wibisono joined the Provisional People's Representative Council as a member of the Masyumi Party.

[8] In March 1951, he even publicly urged the resignation of the Natsir cabinet, citing the failure to arrange a conference on Western New Guinea.

[20] He made public statements calling for the increase of the work day (from seven hours to eight),[21] and was briefly examined by prosecutors after criticizing members of the First Ali Sastroamidjojo Cabinet.

[24] In November 1954, he tabled a motion of no confidence against the Ali Cabinet,[25] in particular attacking the policies of Economic Minister Iskaq Tjokroadisurjo, perceived to be favoring the Indonesian National Party (PNI).

[30] After the end of his ministerial tenure, he was arrested under corruption charges in April 1957, although he was released by March 1958 – officially for a lack of evidence.

Wibisono himself was not involved, and once released wanted to condemn the actions of Natsir and others, but after discussions the party and its members elected to not issue any support or denouncements.

[36][37] He cut ties with nearly all Masyumi leaders except Soekiman, but Wibisono was still arrested in late 1963 or early 1964 under conspiracy charges and was imprisoned for nearly three years without trial.