On January 13, 2011, it was announced Wright had accepted his invitation to play in the 2011 Senior Bowl and was one of four Mississippi State players attending, including Derek Sherrod, Pernell McPhee and Chris White.

On March 10, 2011, Wright attended Mississippi State's pro day and opted to perform all of the drills except the broad jump and bench press.

[9] Wright performed well and impressed coaches throughout training camp and began taking reps at middle linebacker after the unexpected release of Lofa Tatupu in July.

[10] Head coach Carroll named Wright the backup middle linebacker to veteran David Hawthorne to begin the 2011 regular season.

[11] He made his professional regular season debut and first career start in the Seahawks' season-opener at the San Francisco 49ers and recorded five combined tackles during the 33–17 loss.

[13] The next day, defensive coordinator Gus Bradley announced there would be a competition between Wright and Curry for the job as the starting strong side linebacker.

The following day, head coach Carroll stated that the competition for the starting strong side linebacker job between both players remained open.

On October 13, the Seahawks traded Curry to the Oakland Raiders, effectively making Wright the de facto starting strong side linebacker for the remainder of the season.

[15] On December 1, he collected five solo tackles and made his first career sack, on Philadelphia Eagles' quarterback Vince Young during a 31–14 victory.

He started the Seahawks' season opener against the Arizona Cardinals and recorded nine combined tackles and forced the first fumble of his career in a 20–16 loss.

He forced running back Ryan Williams to fumble on the Cardinals' first drive and it was recovered by Seahawks' defensive lineman Brandon Mebane.

In Week 15, he made three combined tackles, deflected a pass, and intercepted quarterback Ryan Fitzpatrick as the Seahawks routed the Buffalo Bills 50–17.

He finished the 2012 season with 98 combined tackles (68 solo), five pass deflections, a sack, an interception, and a fumble recovery in 15 games and 15 starts.

On January 6, 2013, Wright started his first career playoff game and recorded eight combined tackles and a pass deflection during a 24–14 NFC Wildcard victory at the Washington Redskins.

[21] Head coach Carroll named Wagner, Wright, and Malcolm Smith the starting linebackers to begin the regular season.

[23] On September 15, Wright made six combined tackles, defended a pass, and sacked Colin Kaepernick, as the Seahawks routed the San Francisco 49ers 45–17.

After defeating the New Orleans Saints, the Seahawks went on to face the San Francisco 49ers in the NFC Championship with Wright making his return from injury.

On February 2, 2014, Wright started in Super Bowl XLVIII and made seven combined tackles as they routed the Denver Broncos 43–8.

[30] On November 2, 2014, Wright recorded a season-high 13 combined tackles, a pass deflection, and a forced fumble during a 30–24 victory against the Oakland Raiders.

In Week 13, he made seven combined tackles and recorded his first sack on the season on San Francisco 49ers' quarterback Colin Kaepernick in their 19–3 victory.

Wright finished the 2014 season with 107 combined tackles (73 solo), four pass deflections, two sacks, and two forced fumbles in 16 games and 16 starts.

On February 1, 2015, Wright recorded 11 combined tackles as the New England Patriots defeated the Seahawks 28–24 to win Super Bowl XLIX.

Wright shoved Rodgers to the ground and attempted to rip his helmet off and was flagged for unnecessary roughness and immediately ejected from the game.

With less than two minutes remaining in the fourth quarter, Lions' wide receiver Calvin Johnson fumbled the ball at the one-yard line while attempting to dive in the end zone.

The play was scrutinized after ESPN officiating analyst Gerry Austin pointed out the error and explained that the referees failed to penalize Wright for illegal batting that would've given the Lions possession at the one-yard line.

The NFL vice-president of officiating Dean Blandino admitted fault on behalf of the referees and confirmed illegal batting, and that Wright should have been penalized.

[37] Wright started the Seahawks' season-opener against the Miami Dolphins and recorded a season-high 11 combined tackles and sacked quarterback Ryan Tannehill during a 12–10 victory.

[45] Wright recorded 2 combined tackles against the Los Angeles Rams in week 10 but was forced to leave the game early in the second half after aggravating his knee injury.

[54] On September 6, 2021, Wright signed a one-year contract with the Las Vegas Raiders reuniting him with his former Seahawks defensive coordinator Gus Bradley.