Licensed to Jefferson City, Missouri, United States, the station serves the Mid-Missouri area.

The KWOS call sign referenced an earlier Jefferson City radio station, WOS, that was set up by Missouri Agriculture Commissioner Jewell A. Mayes to facilitate agricultural commerce.

[6] Weekday syndicated programming on KWOS includes The Sean Hannity Show, The Glenn Beck Program, Gary Nolan, Coast to Coast AM, The Clay Travis and Buck Sexton Show, Gordon Deal, and Mark Levin.

The station previously aired local religious programming on Sunday mornings until it was removed in 2023.

Syndicated programming on both Saturdays and Sundays include Gordon Deal, Bret Baier, Dave Ramsey, Tom Shillue, Bill Cunningham, and Kim Komando (the only brokered program on KWOS).