KIAA0232

KIAA0232 is located at 4p16.1 neighboring TBC1 domain family member 14 and an uncharacterized locus.

[2] Other notable areas of high expression identified by EST profiling include nerves, umbilical cord, and parathyroid.

KIAA0232 is conserved in most animals, including mammals, reptiles, birds, amphibians, insects, and as far back as Trichnella spiralis, a species of nematode.

It has higher than average frequencies of serine and glutamic acid residues as well as several multi-serine runs that are evolutionarily conserved.

YWHAZ is an apoptotic path regulator known to bind to phosphoserine proteins.