The studios and offices are located on Datapoint Drive in Northwest San Antonio near the South Texas Medical Center complex.

The schedule included dramas, comedies, news, sports and big band broadcasts, during the "Golden Age of Radio."

The simulcast ended in the late 1960s, as the Federal Communications Commission encouraged AM-FM combos to offer separate programming.

KISS-FM began carrying a beautiful music format, including instrumental cover versions of popular songs as well as Broadway and Hollywood show tunes.

[4] Co-owned KMAC broadcast show tunes, opera, as well as religious programs such as the Mormon Tabernacle Choir until noon, when the AM station would simulcast the rock format heard on KISS-FM.

On August 1, 1979, longtime station owner Howard W. Davis died, and eight months later, KMAC and KISS-FM were sold by his estate to Raleigh, North Carolina–based Capitol Broadcasting Company for $4.65 million.

[5] Capitol president James F. Goodmon, upon announcing the sale, said that they were "excited about entering the dynamic San Antonio market and becoming a part of the community".

[5] In 1987, Adams Radio bought KISS-FM for $13 million[6] after a previous sale to Noble Broadcast Group the year before failed to close.

[14] Of note, Cox owns WALR-FM, an urban adult contemporary station in its home city of Atlanta, which utilizes the "KISS-FM" branding.

iHeart has KISS-FM stations in Los Angeles, Chicago (WKSC-FM), Dallas (KHKS), Boston (WXKS-FM), and other cities.