[3] 100.3 signed on the weekend of October 18–19, 1980,[4] as KIKO-FM, owned by Willard "Willy" Shoecraft alongside KIKO, who began operating his FM station from a ridge above Globe (the east end used by the local two-way users).

The station went head to head with KUPD, with high-profile jocks like Madd Maxx Hammer, The G-Ster, Jan Williams, Dangerous Dave Olson, KC Kennedy, Larry Mac, Rob Trygg, Tracy Lea and many other veteran KUPD jocks.

KZRX dropped hard rock for hot talk in early 1995, and applied for the letters KHOT-FM, adding Howard Stern, who was also on KGME.

On September 3, 2010, at 4:30 pm, KQMR 100.3 broke from 106.3's Recuerdo format and flipped to Latin pop as "La Kalle".

On January 2, 2013, KQMR began simulcasting on KHOV-FM 105.1 FM in Wickenburg, Arizona, which covers the West Valley.

On January 15, 2021, KHOV 105.1 was switched back to simulcast KQMR 100.3 covering the west valley once again in the phoenix area.