It starts from a swamp approximately 12 kilometres (7.5 mi), northeast of the village of Kitoma, in Kibaale District, Western Uganda.

[1] River Kafu enters the Victoria Nile near Masindi Port, with coordinates: Latitude:1.6475; Longitude:32.0945.

River Nkusi however, arises elsewhere and passes through the said swamp and flows westwards to empty into Lake Albert, along the International border between Uganda and the Democratic Republic of the Congo.

At its point of entry into River Nile, the altitude is approximately 1,040 metres (3,410 ft).

The length of River Kafu is approximately 180 kilometres (110 mi), from source to end.