[2] The bank was founded in 1983 as a credit trust, Centenary Rural Development Trust (CRDT), by Simeon Lutaakome, Hugh Francis Pulle, Paul Kateregga, Vincent Kirabo kya Maria, Emmanuel Mpande, and John Ogutu.

[4] In May 2009, John Giles left the seat of Managing Director after three years at the position.The current Managing Director is Fabian Kasi[5] In 2011, the Centenary Bank launched a program with the World Bank Group to develop loans in the Ugandan agricultural sector.

Its headquarters building is Mapeera House, on Kampala Road opposite City Square.

[12] In December 2021, Centenary Bank unveiled a Cente Platinum Mastercard, a debit card for its premium customers.

The multinational conglomerate comprises: As of December 2021[update], the bank's stock was privately owned by the following corporate entities and individuals:[16]