Kadoka got its start in 1906 when the Chicago, Milwaukee, St. Paul and Pacific Railroad was extended to that point.

There were 350 housing units at an average density of 152.8 per square mile (59.0/km2).

40.5% of all households were made up of individuals, and 19.6% had someone living alone who was 65 years of age or older.

35.5% of all households were made up of individuals, and 20.1% had someone living alone who was 65 years of age or older.

The Ringneck and Western Railroad operates freight service on the former Milwaukee Road from Kadoka to Mitchell, South Dakota.

The airport is located in the eastern part of the town near the Kadoka school athletic facilities.

The town has a museum that occupies the building that used to be the train station.

Media related to Kadoka, South Dakota at Wikimedia Commons