Kaimana Regency contains over 500 separate offshore islands, spread over the five districts with coastlines.

The inhabitants of Kaimana District, who are local tribes, are the largest population, followed by non-indigenous people (who come from outside areas) who are scattered in several villages in the Kaimana Kota kelurahan, such as Seram and Kaki Air.

Indigenous people are found in the villages inside and outside the urban kaimana kota.

The Kambrau tribe originates from the Teluk Kambrau District, Kaimana District and the Arguni Bay area and is spread across the southern and northern coasts of the Kaimana Kota kelurahan.

Based on data released by the Kaimana Regency Government in 2021, as of January 1, 2021, the majority of the population is Islam, which is 50.63% (generally consists of local coastal Papuans combined with migrants from outside Papua).

Religious followers Christianity are also quite large, namely 49.32% where Protestants are 39.98% and Catholic 9.34% (basically Papuans).